Human SPRY4 Recombinant Protein (N-His) (HP417022)

Name: Human SPRY4 Recombinant Protein (N-His)
Brand: abinScience
SKU: HP417022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HP417022
Description	Recombinant Human SPRY4 Protein, N-His (HP417022) expressed in E. coli, spanning Phe156-Phe299. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q9C004
Protein length	Phe156-Phe299
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	18.04 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Protein sprouty homolog 4, SPRY4, Spry-4
Background	Protein sprouty homolog 4 is a ~32 kDa protein. Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1. Represses integrin-mediated cell spreading via inhibition of TESK1-mediated phosphorylation of cofilin. 1. Leeksma, OC. et al. (2002) European journal of biochemistry 269, 2546-56. PMID: 12027893 2. Sasaki, A. et al. (2003) Nature cell biology 5, 427-32. PMID: 12717443 3. Tsumura, Y. et al. (2005) The Biochemical journal 387, 627-37. PMID: 15584898
Note	For research use only

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Datasheet

Human SPRY4 Recombinant Protein (N-His).pdf

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Human SPRY4 Recombinant Protein (N-His) (HP417022)

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