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| 카탈로그 번호 | HP775022 |
|---|---|
| 설명 |
Recombinant Human TMEM70 Protein, N-GST & C-His (HP775022) expressed in E. coli, spanning Thr163-Lys260. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q9BUB7 |
| 단백질 길이 | Thr163-Lys260 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 39.78 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | TMEM70, Transmembrane protein 70, mitochondrial |
| 배경 | Transmembrane protein 70, mitochondrial is a ~28 kDa protein. Scaffold protein that participates in the c-ring assembly of mitochondrial ATP synthase (F(1)F(0) ATP synthase or complex V) by facilitating the membrane insertion and oligomer formation of the subunit c/ATP5MC1 through its interaction. Therefore, participates in the early stage of mitochondrial ATP synthase biogenesis and also protects subunit c/ATP5MC1 against intramitochondrial proteolysis. In addition, binds the mitochondrial proton-transporting ATP synthase complexes I and may play a role in the stability of its membrane-bound subassemblies. 1. Kovalčíkova, J. et al. (2019) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 33, 14103-14117. PMID: 31652072 2. Sánchez-Caballero, L. et al. (2020) Biochimica et biophysica acta. Bioenergetics 1861, 148202. PMID: 32275929 3. Bahri, H. et al. (2021) Biochimica et biophysica acta. Molecular cell research 1868, 118942. PMID: 33359711 4. Carroll, J. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 33753518 5. Cízková, A. et al. (2008) Nature genetics 40, 1288-90. PMID: 18953340 6. Hejzlarová, K. et al. (2011) Biochimica et biophysica acta 1807, 144-9. PMID: 20937241 |
| 참고사항 | For research use only |
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