Anti-Human TMEM70 Polyclonal Antibody (HP775014)

Name: Anti-Human TMEM70 Polyclonal Antibody
Brand: abinScience
SKU: HP775014
Price: 168 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HP775014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human TMEM70 (Thr163-Lys260).

Target

TMEM70, Transmembrane protein 70, mitochondrial

Purification

Purified by antigen affinity column.

Accession

Q9BUB7

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Transmembrane protein 70, mitochondrial (TMEM70) is a ~28 kDa protein. Scaffold protein that participates in the c-ring assembly of mitochondrial ATP synthase (F(1)F(0) ATP synthase or complex V) by facilitating the membrane insertion and oligomer formation of the subunit c/ATP5MC1 through its interaction. Therefore, participates in the early stage of mitochondrial ATP synthase biogenesis and also protects subunit c/ATP5MC1 against intramitochondrial proteolysis. In addition, binds the mitochondrial proton-transporting ATP synthase complexes I and may play a role in the stability of its membrane-bound subassemblies.

1. Kovalčíkova, J. et al. (2019) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 33, 14103-14117. PMID: 31652072

2. Sánchez-Caballero, L. et al. (2020) Biochimica et biophysica acta. Bioenergetics 1861, 148202. PMID: 32275929

3. Bahri, H. et al. (2021) Biochimica et biophysica acta. Molecular cell research 1868, 118942. PMID: 33359711

4. Carroll, J. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 33753518

5. Cízková, A. et al. (2008) Nature genetics 40, 1288-90. PMID: 18953340

6. Hejzlarová, K. et al. (2011) Biochimica et biophysica acta 1807, 144-9. PMID: 20937241

Note

For research use only.

Images

References

Datasheet

Anti-Human TMEM70 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Assay Kits

Anti-Human TMEM70 Polyclonal Antibody (HP775014)

Overview

Images

References

Datasheet

SDS

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