Human TRIM32 Recombinant Protein (N-GST & C-His) (HC467022)

Name: Human TRIM32 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HC467022
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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개요
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개요

카탈로그 번호	HC467022
설명	Recombinant Human TRIM32 Protein, N-GST & C-His (HC467022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
발현 시스템	E. coli
등록번호	Q13049
단백질 길이	Ser7-Arg101
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	72 kDa Tat-interacting protein, E3 ubiquitin-protein ligase TRIM32, EC:2.3.2.27, HT2A, RING-type E3 ubiquitin transferase TRIM32, TRIM32, Tripartite motif-containing protein 32, Zinc finger protein HT2A
배경	E3 ubiquitin-protein ligase TRIM32 is a ~71 kDa protein. E3 ubiquitin ligase that plays a role in various biological processes including neural stem cell differentiation, innate immunity, inflammatory resonse and autophagy. Plays a role in virus-triggered induction of IFN-beta and TNF by mediating the ubiquitination of STING1. Mechanistically, targets STING1 for 'Lys-63'-linked ubiquitination which promotes the interaction of STING1 with TBK1. Regulates bacterial clearance and promotes autophagy in Mycobacterium tuberculosis-infected macrophages. Negatively regulates TLR3/4-mediated innate immune and inflammatory response by triggering the autophagic degradation of TICAM1 in an E3 activity-independent manner. 1. Locke, M. et al. (2009) Human molecular genetics 18, 2344-58. PMID: 19349376 2. Di Rienzo, M. et al. (2019) Science advances 5, eaau8857. PMID: 31123703 3. Zhang, J. et al. (2012) The Journal of biological chemistry 287, 28646-55. PMID: 22745133 4. Romagnoli, A. et al. (2023) Cell death & disease 14, 505. PMID: 37543647 5. Yang, Q. et al. (2017) PLoS pathogens 13, e1006600. PMID: 28898289 6. Prajapati, P. et al. (2020) Cellular signalling 76, 109777. PMID: 32918979 7. Ryu, YS. et al. (2011) The Journal of biological chemistry 286, 25729-38. PMID: 21628460 8. Zhang, Q. et al. (2012) The Journal of biological chemistry 287, 20625-35. PMID: 22500027 10. Liu, J. et al. (2023) Cell reports 42, 113402. PMID: 37943659
참고사항	For research use only

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Human TRIM32 Recombinant Protein (N-GST & C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Human TRIM32 Recombinant Protein (N-GST & C-His) (HC467022)

개요

이미지

참고 문헌

데이터시트

SDS

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