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| 카탈로그 번호 | HT234012 |
|---|---|
| 설명 |
Recombinant Human ZBTB7B Protein, N-His (HT234012) expressed in E. coli, spanning Asp311-Asp466. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | O15156 |
| 단백질 길이 | Asp311-Asp466 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 20.64 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | Krueppel-related zinc finger protein cKrox, T-helper-inducing POZ/Krueppel-like factor, ZBTB15, ZBTB7B, ZFP67, ZNF857B, Zfp-67, Zinc finger and BTB domain-containing protein 15, Zinc finger and BTB domain-containing protein 7B, Zinc finger protein 67 homolog, Zinc finger protein 857B, Zinc finger protein Th-POK, hcKrox |
| 배경 | Zinc finger and BTB domain-containing protein 7B is a ~58 kDa protein. Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Exerts distinct biological functions in the mammary epithelial cells and T cells in a tissue-specific manner. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Cross-antagonism between ZBTB7B and CBF complexes are determinative to CD4 versus CD8 cell fate decision. 1. Widom, RL. et al. (1997) Gene 198, 407-20. PMID: 9370309 |
| 참고사항 | For research use only |
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