Mouse ACE2 Recombinant Protein (C-Fc) (MV157021)

Name: Mouse ACE2 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: MV157021
Price: 298 USD
Availability: InStock

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50ug
100ug
1mg

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개요

카탈로그 번호	MV157021
설명	Recombinant Mouse ACE2 Protein, C-Fc (MV157021) expressed in Mammalian Cells, spanning Gln18-Thr740. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	Mammalian cells
등록번호	Q8R0I0
단백질 길이	Gln18-Thr740
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Mus musculus (Mouse)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	111.82 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	ACE-related carboxypeptidase, ACE2, ACEH, Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, Angiotensin-converting enzyme-related carboxypeptidase, EC:3.4.17.-, EC:3.4.17.23, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2
배경	Angiotensin-converting enzyme 2 is a ~92 kDa protein. Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis. Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II. Also removes the C-terminal residue from three other vasoactive peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin. Also cleaves other biological peptides, such as apelins, casomorphins and dynorphin A. By cleavage of angiotensin II, may be an important regulator of heart function. 1. Crackower, MA. et al. (2002) Nature 417, 822-8. PMID: 12075344 2. Donoghue, M. et al. (2003) Journal of molecular and cellular cardiology 35, 1043-53. PMID: 12967627 3. Imai, Y. et al. (2005) Nature 436, 112-6. PMID: 16001071 4. Kowalczuk, S. et al. (2008) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22, 2880-7. PMID: 18424768 5. Camargo, SM. et al. (2009) Gastroenterology 136, 872-82. PMID: 19185582 6. Fairweather, SJ. et al. (2012) The Biochemical journal 446, 135-48. PMID: 22677001
참고사항	For research use only

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Mouse ACE2 Recombinant Protein (C-Fc).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Mouse ACE2 Recombinant Protein (C-Fc) (MV157021)

개요

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