Anti-HCV Envelope glycoprotein E2 Reference Antibody (MBL-HCV1, RUO) (VK681016)

Name: Anti-HCV Envelope glycoprotein E2 Reference Antibody (MBL-HCV1, RUO)
Brand: abinScience
SKU: VK681016
Price: 370 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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100ug
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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	VK681016
설명	Anti-HCV NS1/Envelope glycoprotein E2 (MBL-HCV1) (VK681016) is a research-grade recombinant antibody targeting NS1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Hepatitis C Virus (HCV)
응용 분야	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1-kappa
클론 ID	MBL-HCV1
테스트된 응용 분야	WB
타겟	Envelope glycoprotein E2, NS1, gp68, gp70
내독소 수준	< 10 EU/mg
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P27958
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	MBL-HCV1, MBLHCV1
배경	Genome polyprotein (NS1/gp68) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable). 1. Ivanyi-Nagy, R. et al. (2008) Nucleic acids research 36, 712-25. PMID: 18033802 2. Anjum, S. et al. (2013) Molecular medicine reports 8, 487-92. PMID: 23799612 3. Kittlesen, DJ. et al. (2000) The Journal of clinical investigation 106, 1239-49. PMID: 11086025 4. Waggoner, SN. et al. (2007) Journal of leukocyte biology 82, 1407-19. PMID: 17881511 5. Ruggieri, A. et al. (2003) Virus research 97, 103-10. PMID: 14602201
참고사항	For research use only. Not suitable for clinical or therapeutic use.

이미지

Western blot

Western blot analysis was performed using anti-glycoprotein E2 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant hepatitis C virus (Catalog No: VK681011)
Lane 2: negative control
Bioactivity

Detects recombinant HCV NS1/gp68/gp70/Envelope glycoprotein E2 (Catalog No: VK681011) in indirect ELISA