Anti-Human AG-7 Antigen Reference Antibody (AbGn-107, RUO) (HY036106)

Name: Anti-Human AG-7 Antigen Reference Antibody (AbGn-107, RUO)
Brand: abinScience
SKU: HY036106
Price: 176 USD
Availability: InStock

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100ug
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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HY036106

설명

Anti-Human CD71/TFRC (AbGn-107) (HY036106) is a research-grade recombinant antibody targeting CD71. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

종 반응성

Human

응용 분야

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

숙주 종

Human

클론성

Monoclonal

이소타입

IgG1, kappa

클론 ID

AbGn-107

발현 시스템

Mammalian cells

성질

Recombinant

타겟

AG-7, Lewis A-like glycol-epitope

내독소 수준

< 10 EU/mg as determined by LAL method.

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

형태

Liquid

저장 완충액

0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

대체 이름

AbGn-107, AbGn107, AbGn107

배경

Transferrin receptor protein 1 (CD71/TFRC) is a ~84 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the hereditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

1. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738

2. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240

참고사항

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

이미지

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD71/TFRC (AbGn-107).

참고 문헌

데이터시트

Anti-Human AG-7 Antigen Reference Antibody (AbGn-107, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human AG-7 Antigen Reference Antibody (AbGn-107, RUO) (HY036106)

개요

이미지

참고 문헌

데이터시트

SDS