Research Grade hEPO-Fc (HB152016)

Name: Research Grade hEPO-Fc
Brand: abinScience
SKU: HB152016
Price: 370 USD
Availability: InStock

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개요

카탈로그 번호	HB152016
설명	Anti-Human EPOR (rhEPO-Fc) (HB152016) is a research-grade recombinant antibody targeting EPOR. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	Functional assay
숙주 종	Human
발현 시스템	Mammalian cells
종	Homo sapiens (Human)
타겟	EPOR, Erythropoietin receptor, EPO-R
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P01588
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경	Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. _x005F_x005F_x000D_ _x005F_x005F_x000D_ 1. Zhan, H. et al. (1999) Protein engineering 12, 505-13. PMID: 10388848 _x005F_x005F_x000D_ _x005F_x005F_x000D_ 2. Winkelmann, JC. et al. (1990) Blood 76, 24-30. PMID: 2163695 _x005F_x005F_x000D_ _x005F_x005F_x000D_ 3. Jones, SS. et al. (1990) Blood 76, 31-5. PMID: 2163696 _x005F_x005F_x000D_ _x005F_x005F_x000D_ 4. Middleton, SA. et al. (1996) The Journal of biological chemistry 271, 14045-54. PMID: 8662939 _x005F_x005F_x000D_ _x005F_x005F_x000D_ 5. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108 _x005F_x005F_x000D_ _x005F_x005F_x000D_ 6. Kirito, K. et al. (2002) Blood 99, 102-10. PMID: 11756159 _x005F_x005F_x000D_
참고사항	For research use only. Not suitable for clinical or therapeutic use.

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Research Grade hEPO-Fc.pdf

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Research Grade hEPO-Fc (HB152016)

개요

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참고 문헌

데이터시트

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