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Research Grade Efparepoetin Alfa (HF703016)

Research Grade Efparepoetin Alfa
Research Grade Efparepoetin Alfa
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Overview
Catalog No.HF703016
Description
Efparepoetin Alfa (HF703016) is a research-grade recombinant antibody targeting EPO. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Functional assay, Research in vivo
IsotypeHuman erythropoietin fragment fused via peptide linker to a Fc fragment of immunoglobulin G2
Expression system Mammalian cells
Target EPO, Erythropoietin, Epoetin
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P01588
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names2761347-19-5
Background

Erythropoietin (EPO) is a ~21 kDa protein. Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.

1. Kim, AR. et al. (2017) Cell 168, 1053-1064.e15. PMID: 28283061
2. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Research Grade Efparepoetin Alfa

    SDS-PAGE

    SDS-PAGE for Research Grade Efparepoetin Alfa

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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