Anti-Human OSM/Oncostatin-M Reference Antibody (GSK315234, RUO) (HB745026)

Name: Anti-Human OSM/Oncostatin-M Reference Antibody (GSK315234, RUO)
Brand: abinScience
SKU: HB745026
Price: 176 USD
Availability: InStock

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HB745026
설명	Anti-Human OSM/Oncostatin-M (GSK315234) (HB745026) is a research-grade recombinant antibody targeting Oncostatin-M. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1-kappa
클론 ID	GSK315234
발현 시스템	Mammalian cells
테스트된 응용 분야	WB, FCM
타겟	Oncostatin-M, OSM
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P13725
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	GSK315234
배경	Oncostatin-M (OSM) is a ~28 kDa protein. Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST).
참고사항	For research use only. Not suitable for clinical or therapeutic use.

이미지

Western blot

Western blot analysis was performed using anti-OSM monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human OSM (Catalog No: HB745011)
Lane 2: negative control
Bioactivity

Detects recombinant human OSM/Oncostatin-M (Catalog No: HB745011) in indirect ELISA
Flow cytometry

Flow-cytometry using anti-human OSM antibody. KG-1 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human OSM monoclonal antibody (Catalog HB745026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.