Anti-Human PIGF Reference Antibody (RO5323441, RUO) (HW315036)

Name: Anti-Human PIGF Reference Antibody (RO5323441, RUO)
Brand: abinScience
SKU: HW315036
Price: 176 USD
Availability: InStock

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개요

카탈로그 번호	HW315036
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG
클론 ID	RO5323441
발현 시스템	Mammalian cells
타겟	PLGF, PGF, PlGF, PGFL, Placenta growth factor
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P49763
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	RO5323441
배경	Placenta growth factor (PGF/PLGF) is a ~24 kDa protein. Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
참고 문헌	1. Rizzo C, et al. RO5323441, a humanized monoclonal antibody against the placenta growth factor, blocks PlGF-induced VEGFR-1 phosphorylation in vitro and tumor growth in vivo[J]. Cancer Research, 2010, 70(8_Supplement): 1370-1370. [HW315036]
참고사항	For research use only. Not suitable for clinical or therapeutic use.

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데이터시트

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