Anti-Human Siglec-8 Reference Antibody (1H10, RUO) (HP983026)

Name: Anti-Human Siglec-8 Reference Antibody (1H10, RUO)
Brand: abinScience
SKU: HP983026
Price: 370 USD
Availability: InStock

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개요

카탈로그 번호	HP983026
설명	Anti-Human SIGLEC8/SAF-2 Antibody (1H10) (HP983026) is a research-grade recombinant antibody targeting SAF2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1
클론 ID	1H10
발현 시스템	Mammalian cells
성질	Recombinant
타겟	SAF2, Sialoadhesin family member 2, SAF-2, Siglec-8, SIGLEC8, Sialic acid-binding Ig-like lectin 8
내독소 수준	< 10 EU/mg as determined by LAL method.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q9NYZ4
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경	Sialic acid-binding Ig-like lectin 8 (SIGLEC8/SAF-2) is a ~54 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose. 1. Floyd, H. et al. (2000) The Journal of biological chemistry 275, 861-6. PMID: 10625619 2. Kikly, KK. et al. (2000) The Journal of allergy and clinical immunology 105, 1093-100. PMID: 10856141 3. Pröpster, JM. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, E4170-9. PMID: 27357658
참고사항	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human SIGLEC8/SAF-2 Antibody (1H10)

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Anti-Human Siglec-8 Reference Antibody (1H10, RUO).pdf

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Anti-Human Siglec-8 Reference Antibody (1H10, RUO) (HP983026)

개요

이미지

참고 문헌

데이터시트

SDS