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| 카탈로그 번호 | HY546036 |
|---|---|
| 설명 |
Cibisatamab (HY546036) is a research-grade recombinant antibody targeting CD66. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG1-kappa/lambdawithdomaincrossover |
| 타겟 | CD66e, CEA, CEA cell adhesion molecule 5, CEACAM5, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Cell adhesion molecule CEACAM5, Meconium antigen 100, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P06731& P07766 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | Bispecific, CEATCB, RG-7802, RO-6958688, 2101242-53-7 |
| 배경 | Cibisatamab (CEA-TCB), a T cell bispecific antibody, binds Carcino-Embryonic Antigen (CEA) on cancer cells and CD3 on T cells. Cibisatamab (CEA-TCB) triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. Cibisatamab (CEA-TCB) can be used for colorectal cancer research. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
Detects Human CD66e/CEA/CEACAM5 & CD3E separately in indirect ELISAs.
Detects Human CD66e/CEA/CEACAM5 & CD3E separately in indirect ELISAs.
SDS-PAGE for Research Grade Cibisatamab.
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
