

| Catalog No. | HY546126 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| Host species | Human | ||||
| Isotype | BiTE | ||||
| Clone ID | MEDI-565 | ||||
| Expression system | Mammalian cells | ||||
| Clonality | Monoclonal | ||||
| Target | Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen, CEA, Meconium antigen 100, CD66e, CEACAM5, CEA, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T3E | ||||
| Endotoxin level | Please contact the lab for this information. | ||||
| Purity | >95% purity as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P06731 & P07766 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
| ||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Alternate Names | Bispecific, AMG-211, AMG211, AMG211, MT-111, MT111, MT111, MEDI565, MEDI565 | ||||
| References | 1. Moek KL, et al. 89Zr-labeled Bispecific T-cell Engager AMG 211 PET Shows AMG 211 Accumulation in CD3-rich Tissues and Clear, Heterogeneous Tumor Uptake. Clin Cancer Res. 2019 Jun 15;25(12):3517-3527. [HY546126] | ||||
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Anti-Human CEACAM-5/CD66e & CD3 Bispecific Reference Antibody (MEDI-565, RUO)
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