Anti-Human CEACAM-5/CD66e & CD3 epsilon Bispecific Reference Antibody (Cibisatamab, RUO) (HY546036)

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100ug
1mg

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Overview

Catalog No.	HY546036
Description	Cibisatamab (HY546036) is a research-grade recombinant antibody targeting CD66. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Humanized
Isotype	IgG1-kappa/lambdawithdomaincrossover
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P06731 & P07766
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Bispecific, CEATCB, RG-7802, RO-6958688, 2101242-53-7
Background	Cibisatamab (CEA-TCB), a T cell bispecific antibody, binds Carcino-Embryonic Antigen (CEA) on cancer cells and CD3 on T cells. Cibisatamab (CEA-TCB) triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. Cibisatamab (CEA-TCB) can be used for colorectal cancer research.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects Human CD66e/CEA/CEACAM5 & CD3E separately in indirect ELISAs.
Bioactivity

Detects Human CD66e/CEA/CEACAM5 & CD3E separately in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Cibisatamab.

References

Datasheet

Anti-Human CEACAM-5/CD66e & CD3 epsilon Bispecific Reference Antibody (Cibisatamab, RUO).pdf

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Formula

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Recombinant Proteins

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Anti-Human CEACAM-5/CD66e & CD3 epsilon Bispecific Reference Antibody (Cibisatamab, RUO) (HY546036)

Overview

Images

References

Datasheet

SDS

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