Research Grade Efgivanermin Alfa (HV475036)

Name: Research Grade Efgivanermin Alfa
Brand: abinScience
SKU: HV475036
Price: 424 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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100ug
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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HV475036
설명	Efgivanermin Alfa (HV475036) is a research-grade recombinant antibody targeting CD357. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Functional assay, Research in vivo
이소타입	Fusion - [IGHG1 Fc (Fragment constant) - [CORO1A (coronin 1A, actin-binding protein) - TNFSF18 (TNF superfamily member 18, AITRL, TL6, GITRL)]2]3 (hexamer)
발현 시스템	Mammalian cells
타겟	Activation-inducible TNFR family receptor, GITR, TNFRSF18, CD357, Tumor necrosis factor receptor superfamily member 18, AITR, Glucocorticoid-induced TNFR-related protein
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q9Y5U5
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	MEDI-1873, MEDI1873, 1807864-13-6
배경	Tumor necrosis factor receptor superfamily member 18 (CD357/GITR) is a ~26 kDa protein. Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
참고사항	For research use only. Not suitable for clinical or therapeutic use.