Anti-RABV Glycoprotein G Reference Antibody (Foravirumab, RUO) (VK632016)

Name: Anti-RABV Glycoprotein G Reference Antibody (Foravirumab, RUO)
Brand: abinScience
SKU: VK632016
Price: 176 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
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개요

카탈로그 번호	VK632016
설명	Foravirumab (VK632016) is a research-grade recombinant antibody targeting G/Glycoprotein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Rabies virus (RABV)
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1, kappa
발현 시스템	Mammalian cells
타겟	G/Glycoprotein
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	O92284
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	CR4098, 944548-38-3
배경	Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
참고사항	For research use only. Not suitable for clinical or therapeutic use.