Anti-Rabies virus/RABV G/Glycoprotein Polyclonal Antibody (VK632014)

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50ug
100ug

Number:

Overview
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Datasheet
SDS

Overview

Catalog No.

VK632014

Description

Anti-Rabies virus/RABV G/Glycoprotein Polyclonal Antibody (VK632014) is a rabbit polyclonal antibody detecting Glycoprotein in ELISA, IHC, WB. Suitable for Rabies virus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Rabies virus

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Rabies virus/RABV G/Glyco(Leu30-Tyr459).

Target

Glycoprotein, G

Purification

Purified by antigen affinity column.

Accession

O92284

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Rabies virus/RABV G/Glycoprotein polyclonal antibody at 1ug/mL on recombinant Rabies virus/RABV G/Glycoprotein (Catalog No. VK632012).
Western blot

Western blot analysis was performed using anti-RABV-G polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Rabies virus/RABV G/Glycoprotein (Catalog No: VK632012)