中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HV612046 |
|---|---|
| 설명 |
Obrindatamab (HV612046) is a research-grade recombinant antibody targeting CD276. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | scFv with Domain Crossover, Kappa;Lambda |
| 테스트된 응용 분야 | WB |
| 타겟 | 4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | Q5ZPR3 & P07766 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | Bispecific, MGD009, RES281M1.1, hBRCA84D-hXR32-MP3M1.1, 2069959-72-2 |
| 배경 | Obrindatamab is a humanized anti-B7-H3/CD3 bispecific antibody. Obrindatamab binds to B7-H3 and CD3, thereby mediating redirected cytotoxic T-lymphocyte (CTL) activity against B7-H3-expressing cancer cells. Obrindatamab can be used in research of cancer. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
SDS-PAGE for Research Grade Obrindatamab
Detects CD276 in indirect ELISAs.
Detects CD3E in indirect ELISAs.
Detects CD276 in indirect ELISA.
Detects Recombinant Human CD276 Protein, C-His (Cat No.: HV612011) in indirect ELISA.
Western blot analysis was performed using anti-CD276 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD276 (Catalog No: HV612011)
Lane 2: negative control
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
