Anti-Human PD-1 & PD-L1 Bispecific Reference Antibody (Reozalimab, RUO) (HV974216)

Name: Anti-Human PD-1 & PD-L1 Bispecific Reference Antibody (Reozalimab, RUO)
Brand: abinScience
SKU: HV974216
Price: 400 USD
Availability: InStock

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개요

카탈로그 번호	HV974216
설명	Reozalimab (HV974216) is a research-grade recombinant antibody targeting CD1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	Ig(G1-kappa_G1-lambda2)
테스트된 응용 분야	WB, FCM
타겟	B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1, CD279, PD1, PDCD1, Programmed cell death protein 1, Protein PD-1
내독소 수준	< 10 EU/mg
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q9NZQ7 & Q15116
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	Bispecific, IBI318, IBI-318, IBI318, 2445259-99-2
배경	Reozalimab is a bispecific antibody targeting to PD-1/PD-L1. Reozalimab mediates antibody-dependent cell cytotoxicity in cancer research.
참고사항	For research use only. Not suitable for clinical or therapeutic use.

이미지

Bioactivity

Detects PDL1 in indirect ELISA.
Bioactivity

Detects recombinant human PD1 (Cat No.: HS870021) in indirect ELISA.
Flow CytoMetry

Flow-cytometry using anti-human CD274 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD274 monoclonal antibody (Catalog: HV974216) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-CD274/PD-L1/B7-H1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD274/PD-L1/B7-H1 (Catalog No: HV974011)
Lane 2: negative control

참고 문헌

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Anti-Human PD-1 & PD-L1 Bispecific Reference Antibody (Reozalimab, RUO).pdf

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Formula

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Anti-Human PD-1 & PD-L1 Bispecific Reference Antibody (Reozalimab, RUO) (HV974216)

개요

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참고 문헌

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