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| 카탈로그 번호 | JN968016 |
|---|---|
| 설명 |
SYN-005-1B7 (JN968016) is a research-grade recombinant antibody targeting ptxAPTXS1. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Bordetella pertussis |
| 응용 분야 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG1-kappa |
| 발현 시스템 | Mammalian cells |
| 타겟 | ptxAPTXS1 |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% purity as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P04977 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | hu1B7, SYN-005, SYN-005-1B7 |
| 배경 | Pertussis toxin subunit 1 (ptxAPTXS1) is a ~29 kDa protein. S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade SYN-005-1B7
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
