Anti-Human PAUF Reference Antibody (Ulenistamab, RUO) (HB774016)

Name: Anti-Human PAUF Reference Antibody (Ulenistamab, RUO)
Brand: abinScience
SKU: HB774016
Price: 176 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호	HB774016
설명	Ulenistamab (HB774016) is a research-grade recombinant antibody targeting PAUF. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1-kappa
발현 시스템	Mammalian cells
성질	Recombinant
타겟	PAUF
내독소 수준	< 10 EU/mg as determined by LAL method.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q96DA0
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	PBP1510, PBP-1510, PBP15102415259-90-2
배경	Pancreatic adenocarcinoma up-regulated factor (PAUF) is a ~18 kDa protein. Functions as a lectin that binds to selective commensal dental plaque bacteria, such as Streptococcus vestibularis. Contributes to maintain homeostasis in the oral microbiome by capturing commensal microbes and regulating their growth using a mucin-assisted clearance mechanism. Plays an important role in pancreatic tumor progression and metastasis. Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kappaB signaling pathway, without the involvement of the TLR4/TRIF pathway. 1. Ghosh, S. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2216304120. PMID: 37216558 2. Kim, SA. et al. (2009) Cancer science 100, 828-36. PMID: 19302292 3. Youn, SE. et al. (2022) International journal of molecular sciences 23. PMID: 36232715
참고사항	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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SDS-PAGE

SDS-PAGE for Research Grade Ulenistamab.

참고 문헌

데이터시트

Anti-Human PAUF Reference Antibody (Ulenistamab, RUO).pdf

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Formula

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어세이 키트

Anti-Human PAUF Reference Antibody (Ulenistamab, RUO) (HB774016)

개요

이미지

참고 문헌

데이터시트

SDS