

| 카탈로그 번호 | HC554014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-AIMP1 Polyclonal Antibody (HC554014) is a rabbit polyclonal antibody detecting AIMP1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Cricetulus griseus.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human AIMP1 (Lys148-Lys312). | ||||||||
| 타겟 | AIMP1, Endothelial monocyte-activating polypeptide II, EMAP-II, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, EMAP-2, SCYE1, EMAP2, Multisynthase complex auxiliary component p43, Small inducible cytokine subfamily E member 1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q12904 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1/EMAP-II) is a ~34 kDa protein. Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. 1. Park, SG. et al. (1999) The Journal of biological chemistry 274, 16673-6. PMID: 10358004 2. Shalak, V. et al. (2001) The Journal of biological chemistry 276, 23769-76. PMID: 11306575 3. Han, JM. et al. (2006) Biochemical and biophysical research communications 342, 113-8. PMID: 16472771 4. Park, SG. et al. (2002) The Journal of biological chemistry 277, 45243-8. PMID: 12237313 5. Park, H. et al. (2002) Journal of leukocyte biology 71, 223-30. PMID: 11818442 6. Tandle, AT. et al. (2009) Experimental cell research 315, 1850-9. PMID: 19362550 | ||||||||
| 참고사항 | For research use only. |
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