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Anti-Human AIMP1/EMAP-II Recombinant Antibody (SAA1810) (HC554013)

Anti-Human AIMP1/EMAP-II Recombinant Antibody (SAA1810)
Anti-Human AIMP1/EMAP-II Recombinant Antibody (SAA1810)
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Overview
Catalog No.HC554013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA1810
Clonality Monoclonal
Target AIMP1, Endothelial monocyte-activating polypeptide II, EMAP-II, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, EMAP-2, SCYE1, EMAP2, Multisynthase complex auxiliary component p43, Small inducible cytokine subfamily E member 1
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q12904
RRID Anti-Human AIMP1/EMAP-II Antibody (SAA1810) (abinScience Cat# HC554013, RRID:AB_3727572)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1/EMAP-II) is a ~34 kDa protein. Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation.

1. Park, SG. et al. (1999) The Journal of biological chemistry 274, 16673-6. PMID: 10358004
2. Shalak, V. et al. (2001) The Journal of biological chemistry 276, 23769-76. PMID: 11306575
3. Han, JM. et al. (2006) Biochemical and biophysical research communications 342, 113-8. PMID: 16472771
4. Park, SG. et al. (2002) The Journal of biological chemistry 277, 45243-8. PMID: 12237313
5. Park, H. et al. (2002) Journal of leukocyte biology 71, 223-30. PMID: 11818442
6. Tandle, AT. et al. (2009) Experimental cell research 315, 1850-9. PMID: 19362550
Note For research use only.
Images
  • Anti-Human AIMP1/EMAP-II Recombinant Antibody (SAA1810)

    SDS-PAGE

    SDS-PAGE for Anti-Human AIMP1/EMAP-II Antibody (SAA1810)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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