Anti-Human Endoglin/CD105 Polyclonal Antibody (HB604014)

Name: Anti-Human Endoglin/CD105 Polyclonal Antibody
Brand: abinScience
SKU: HB604014
Price: 168 USD
Availability: InStock

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개요

카탈로그 번호

HB604014

설명

Anti-CD105/ENG Polyclonal Antibody (HB604014) is a rabbit polyclonal antibody detecting CD105 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CD105/ENG (Thr27-Gly581).

타겟

CD105, END, Endoglin, ENG

정제

Purified by antigen affinity column.

등록번호

P17813

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.

1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454

2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529

3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484

4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773

5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830

6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366

7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410

참고사항

For research use only.

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