Anti-Human CD321/F11R Polyclonal Antibody (HV592014)

Name: Anti-Human CD321/F11R Polyclonal Antibody
Brand: abinScience
SKU: HV592014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HV592014

설명

Anti-CD321/F11R Polyclonal Antibody (HV592014) is a rabbit polyclonal antibody detecting CD321 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CD321/F11R (Phe64-Leu249).

타겟

PAM-1, JAM1, Platelet F11 receptor, JCAM, JAM-A, F11R, Junctional adhesion molecule A, Junctional adhesion molecule 1, CD321, Platelet adhesion molecule 1, JAM-1

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

Q9Y624

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Junctional adhesion molecule A (CD321/F11R) is a ~32 kDa protein. Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration.

1. Itoh, M. et al. (2001) The Journal of cell biology 154, 491-7. PMID: 11489913

2. Ostermann, G. et al. (2002) Nature immunology 3, 151-8. PMID: 11812992

3. Sobocka, MB. et al. (2000) Blood 95, 2600-9. PMID: 10753840

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human CD321/F11R Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CD321/F11R Polyclonal Antibody (HV592014)

개요

이미지

참고 문헌

데이터시트

SDS

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