Anti-Human CD321/F11R/JAM-A Recombinant Antibody (SAA1942) (HV592013)

Name: Anti-Human CD321/F11R/JAM-A Recombinant Antibody (SAA1942)
Brand: abinScience
SKU: HV592013
Price: 196 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV592013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1942

Clonality

Monoclonal

Target

PAM-1, JAM1, Platelet F11 receptor, JCAM, JAM-A, F11R, Junctional adhesion molecule A, Junctional adhesion molecule 1, CD321, Platelet adhesion molecule 1, JAM-1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9Y624

RRID

Anti-Human CD321/F11R/JAM-A Antibody (SAA1942) (abinScience Cat# HV592013, RRID:AB_3727706)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Junctional adhesion molecule A (CD321/F11R) is a ~32 kDa protein. Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration.

1. Itoh, M. et al. (2001) The Journal of cell biology 154, 491-7. PMID: 11489913

2. Ostermann, G. et al. (2002) Nature immunology 3, 151-8. PMID: 11812992

3. Sobocka, MB. et al. (2000) Blood 95, 2600-9. PMID: 10753840

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CD321/F11R/JAM-A Antibody (SAA1942)

References

Datasheet

Anti-Human CD321/F11R/JAM-A Recombinant Antibody (SAA1942).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CD321/F11R/JAM-A Recombinant Antibody (SAA1942) (HV592013)

Overview

Images

References

Datasheet

SDS

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