Human CD321/F11R Recombinant Protein (C-His) (HV592021)

Name: Human CD321/F11R Recombinant Protein (C-His)
Brand: abinScience
SKU: HV592021
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	HV592021
Description	Recombinant Human CD321/F11R Protein, C-His (HV592021) expressed in Mammalian Cells, spanning Ser28-Ala242. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q9Y624
Protein length	Ser28-Ala242
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	26.21 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CD321, F11R, JAM-1, JAM-A, JAM1, JCAM, Junctional adhesion molecule 1, Junctional adhesion molecule A, PAM-1, Platelet F11 receptor, Platelet adhesion molecule 1
Background	Junctional adhesion molecule A is a ~32 kDa protein. Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. 1. Itoh, M. et al. (2001) The Journal of cell biology 154, 491-7. PMID: 11489913 2. Ostermann, G. et al. (2002) Nature immunology 3, 151-8. PMID: 11812992 3. Sobocka, MB. et al. (2000) Blood 95, 2600-9. PMID: 10753840
Note	For research use only