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| 카탈로그 번호 | HY088053 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Rabbit | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | VHH-Fc | ||||
| 클론 ID | SAA2585 | ||||
| 타겟 | HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q9Y3Q4 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) is a ~129 kDa protein. Hyperpolarization-activated ion channel that are permeable to Na(+) and K(+) ions with very slow activation and inactivation. Exhibits higher selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat (Probable). Contributes to the native pacemaker currents in neurons (Ih) (Probable). May mediate responses to sour stimuli. 1. Ludwig, A. et al. (1999) The EMBO journal 18, 2323-9. PMID: 10228147 2. Seifert, R. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 9391-6. PMID: 10430953 3. Xu, X. et al. (2010) The Journal of biological chemistry 285, 37082-91. PMID: 20829353 4. Milanesi, R. et al. (2006) The New England journal of medicine 354, 151-7. PMID: 16407510 5. Ueda, K. et al. (2009) Journal of human genetics 54, 115-21. PMID: 19165230 | ||||
| 참고사항 | For research use only |
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