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| 카탈로그 번호 | VK665014 | ||||||||
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| 설명 |
Anti-HHV-5/HCMV glycoprotein H/gH Polyclonal Antibody (VK665014) is a rabbit polyclonal antibody detecting HHV-5/HCMV glycoprotein H/gH. Suitable for Human cytomegalovirus.
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| 종 반응성 | Human cytomegalovirus (HCMV) (HHV-5) (Human herpesvirus 5) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant HHV-5/HCMV glycoprotein H/gH (Phe298-Val605). | ||||||||
| 타겟 | Envelope glycoprotein H, UL75, gH | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P12824 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Envelope glycoprotein H (gH) is a ~84 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distinct complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA, and in glioblastoma cells by interacting with host EPHA2. | ||||||||
| 참고사항 | For research use only |
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