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Anti-Human CD148 Recombinant Antibody (AB-2), APC (HC363137)

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  • 개요

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개요
카탈로그 번호HC363137
종 반응성Human
응용 분야FCM
숙주 종Mouse
클론성Monoclonal
이소타입IgG1, kappa
클론 IDAB-2
접합APC
타겟 HPTP eta, R-PTP-J, Protein-tyrosine phosphatase eta, Density-enhanced phosphatase 1, Receptor-type tyrosine-protein phosphatase eta, Protein-tyrosine phosphatase receptor type J, DEP-1, R-PTP-eta, CD148, PTPRJ, DEP1
내독소 수준 Please contact with the lab for this information.
관련 제품 Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
등록번호 Q12913
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

안정성 및 저장 Store at 4°C for 12 months. Protect from light. Do not freeze.
배경

Receptor-type tyrosine-protein phosphatase eta (CD148/PTPRJ) is a ~145 kDa protein. Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Has a role in megakaryocytes and platelet formation. Involved in vascular development. Regulator of macrophage adhesion and spreading.

1. Kovalenko, M. et al. (2000) The Journal of biological chemistry 275, 16219-26. PMID: 10821867
2. Persson, C. et al. (2002) FEBS letters 517, 27-31. PMID: 12062403
3. Holsinger, LJ. et al. (2002) Oncogene 21, 7067-76. PMID: 12370829
4. Palka, HL. et al. (2003) The Journal of biological chemistry 278, 5728-35. PMID: 12475979
5. Tsuboi, N. et al. (2008) The Biochemical journal 413, 193-200. PMID: 18348712
6. Sacco, F. et al. (2009) The Journal of biological chemistry 284, 22048-22058. PMID: 19494114
7. Omerovic, J. et al. (2010) The Biochemical journal 426, 65-72. PMID: 19922411
8. Arora, D. et al. (2011) The Journal of biological chemistry 286, 10918-29. PMID: 21262971
9. Kellie, S. et al. (2004) Journal of cell science 117, 609-18. PMID: 14709717
참고사항 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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