Anti-Human CD158k/KIR3DL2 Recombinant Antibody (SAA0064), FITC (HW633117)

Name: Anti-Human CD158k/KIR3DL2 Recombinant Antibody (SAA0064), FITC
Brand: abinScience
SKU: HW633117
Price: 223 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
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개요

카탈로그 번호	HW633117
종 반응성	Human
응용 분야	FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	SAA0064
접합	FITC
타겟	CD158K, MHC class I NK cell receptor, NKAT4, Natural killer-associated transcript 4, KIR3DL2, p70 NK receptor CL-5, CD158k, p70 natural killer cell receptor clone CL-5, CD158 antigen-like family member K, Killer cell immunoglobulin-like receptor 3DL2, NKAT-4
내독소 수준	Please contact with the lab for this information.
관련 제품	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC
등록번호	P43630
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Killer cell immunoglobulin-like receptor 3DL2 (CD158k/KIR3DL2) is a ~50 kDa protein. Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. 1. Goodridge, JP. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 191, 3553-62. PMID: 24018270 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 3. Song, S. et al. (2016) Nature medicine 22, 397-403. PMID: 26928464
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.