Anti-Human CD218a/IL18R1 Recombinant Antibody (1G12), APC (HC691137)

Name: Anti-Human CD218a/IL18R1 Recombinant Antibody (1G12), APC
Brand: abinScience
SKU: HC691137
Price: 290 USD
Availability: InStock

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개요

카탈로그 번호	HC691137
종 반응성	Human
응용 분야	FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	1G12
접합	APC
타겟	CD218a, IL-18R1, IL18R1, CDw218a, IL-18R-alpha, IL-18R-1, Interleukin-18 receptor 1, IL-18Ralpha, IL1 receptor-related protein, CD218 antigen-like family member A, IL-1Rrp, IL1RRP, IL1R-rp, Interleukin-18 receptor alpha
내독소 수준	Please contact with the lab for this information.
관련 제품	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
등록번호	Q13478
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Interleukin-18 receptor 1 (CD218a/IL18R1) is a ~62 kDa protein. Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3. 1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293 2. Wei, H. et al. (2014) FEBS letters 588, 3838-43. PMID: 25261253 3. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532 4. Shi, X. et al. (2023) Nature 624, 442-450. PMID: 37993714 5. Parnet, P. et al. (1996) The Journal of biological chemistry 271, 3967-70. PMID: 8626725 6. Tominaga, K. et al. (2000) International immunology 12, 151-60. PMID: 10653850
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD218a/IL18R1 Recombinant Antibody (1G12), APC.pdf

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Anti-Human CD218a/IL18R1 Recombinant Antibody (1G12), APC (HC691137)

개요

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