Anti-Human CD50/ICAM3 Recombinant Antibody (SAA1382), APC (HW443137)

Name: Anti-Human CD50/ICAM3 Recombinant Antibody (SAA1382), APC
Brand: abinScience
SKU: HW443137
Price: 256 USD
Availability: InStock

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개요
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개요

카탈로그 번호	HW443137
종 반응성	Human
응용 분야	FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1
클론 ID	SAA1382
접합	APC
타겟	CD50, CDw50, Intercellular adhesion molecule 3, ICAM-R, ICAM3, ICAM-3
내독소 수준	Please contact with the lab for this information.
관련 제품	Mouse IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
등록번호	P32942
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Intercellular adhesion molecule 3 (CD50/ICAM3) is a ~59 kDa protein. Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring apoptotic neutrophil phagocytosis by macrophages. Is also a ligand for integrin ITGAD/ITGB2. Ligand of CD209 on dendritic cells (DC) through an integrin-independent mechanism that requires Ca(2+) and that forms a first contact between DC and resting T cell, facilitating the downstream DC-T cell clustering process and DC-induced proliferation of resting T Cells. 1. Fawcett, J. et al. (1992) Nature 360, 481-4. PMID: 1448173 2. Vazeux, R. et al. (1992) Nature 360, 485-8. PMID: 1448174 3. Kristóf, E. et al. (2013) Apoptosis : an international journal on programmed cell death 18, 1235-51. PMID: 23775590 4. Juan, M. et al. (1993) European journal of immunology 23, 1508-12. PMID: 8325327 5. de Fougerolles, AR. et al. (1993) The Journal of experimental medicine 177, 1187-92. PMID: 8459213 6. Van der Vieren, M. et al. (1995) Immunity 3, 683-90. PMID: 8777714 7. Geijtenbeek, TB. et al. (2000) Cell 100, 575-85. PMID: 10721994
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

이미지

Flow CytoMetry

Flow-cytometry using APC anti-human CD50 antibody. RPMI-8226 cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD50 monoclonal antibody (Catalog: HW443137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

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