Anti-Human EMP2 Polyclonal Antibody (HX012014)

Name: Anti-Human EMP2 Polyclonal Antibody
Brand: abinScience
SKU: HX012014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HX012014

설명

Anti-Human EMP2 Polyclonal Antibody (HX012014) is a rabbit polyclonal antibody detecting Epithelial membrane protein 2; EMP-2; Protein XMP; EMP2; XMP in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human EMP2 (Ile21-Thr67).

타겟

Epithelial membrane protein 2; EMP-2; Protein XMP; EMP2; XMP

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P54851

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Epithelial membrane protein 2 (EMP2) is a ~19 kDa protein. Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the alveolar lumen, potentially via mediation of cell surface expression of adhesion markers and lipid raft formation. Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation. Facilitates surface trafficking and formation of lipid rafts bearing GPI-anchor proteins.

1. Gee, HY. et al. (2014) American journal of human genetics 94, 884-90. PMID: 24814193

2. Wadehra, M. et al. (2005) Developmental biology 287, 336-45. PMID: 16216233

3. Morales, SA. et al. (2013) Investigative ophthalmology & visual science 54, 2367-72. PMID: 23439602

4. Fu, M. et al. (2011) PloS one 6, e19945. PMID: 21637765

5. Morales, SA. et al. (2012) Experimental eye research 102, 10-6. PMID: 22728127

6. Morales, SA. et al. (2009) Investigative ophthalmology & visual science 50, 4949-56. PMID: 19494199

7. Wilson, HL. et al. (2002) The Journal of biological chemistry 277, 34017-23. PMID: 12107182

8. Gordon, LK. et al. (2013) Oncogene 32, 5369-76. PMID: 23334331

9. Wadehra, M. et al. (2006) Developmental biology 292, 430-41. PMID: 16487956

참고사항

For research use only

이미지

Western blot

Lane 1: Mouse spleen lysate

참고 문헌

데이터시트

Anti-Human EMP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human EMP2 Polyclonal Antibody (HX012014)

개요

이미지

참고 문헌

데이터시트

SDS