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| 카탈로그 번호 | MC472013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse | ||||
| 응용 분야 | ELISA, Blocking | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1, lambda | ||||
| 클론 ID | SAA2230 | ||||
| 타겟 | IL24 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% purity as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q925S4 | ||||
| RRID | Anti-Mouse IL24 antibody (SAA2230) (abinScience Cat# MC472013, RRID:AB_3729826) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. | ||||
| 대체 이름 | MDA7, MDA-7, ST16, IL-24, Melanoma differentiation-associated gene 7 protein, Suppression of tumorigenicity 16 protein, IL24, Interleukin-24 | ||||
| 배경 | Interleukin-24 (IL24) is a ~25 kDa protein. Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I interferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal. 1. Wang, J. et al. (2020) Cell death & disease 11, 17. PMID: 31907348 2. Davidson, S. et al. (2022) Science immunology 7, eabi6763. PMID: 35148201 | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Human IgG1, lambda Isotype Control antibody (HyHEL-10) (HP248107) |
SDS-PAGE for Anti-Mouse IL24 antibody (SAA2230)
Detects recombinant mouse IL24 (Catalog No: MC472012) in indirect ELISA
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