中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | JN930023 | ||||||
|---|---|---|---|---|---|---|---|
| 종 반응성 | Mycobacterium tuberculosis | ||||||
| 응용 분야 | ELISA, WB | ||||||
| 숙주 종 | Human | ||||||
| 클론성 | Monoclonal | ||||||
| 이소타입 | VHH-hFc | ||||||
| 클론 ID | SAA2568 | ||||||
| 타겟 | EC:4.1.3.1, ICL, Isocitrase, Isocitratase, Isocitrate lyase, icl | ||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||||
| 등록번호 | P9WKK7 | ||||||
| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||||
| 제품 사용 정보 |
| ||||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 배경 | Isocitrate lyase (icl1/Isocitrate lyase 1) is a ~47 kDa protein. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. It could also catalyze the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route). 1. Sharma, V. et al. (2000) Nature structural biology 7, 663-8. PMID: 10932251 2. McKinney, JD. et al. (2000) Nature 406, 735-8. PMID: 10963599 3. Kumar, R. et al. (2008) Proteins 72, 892-900. PMID: 18275086 4. Moynihan, MM. et al. (2014) Biochemistry 53, 178-87. PMID: 24354272 | ||||||
| 참고사항 | For research use only |
SDS-PAGE for Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Antibody (SAA2568)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
