中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | JN930024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mycobacterium tuberculosis Isocitrate lyase/ICL Polyclonal Antibody (JN930024) is a rabbit polyclonal antibody detecting Isocitrate lyase. Suitable for Mycobacterium tuberculosis and Mycobacterium bovis.
Highlights
|
||||||||
| 종 반응성 | Mycobacterium tuberculosis, Mycobacterium bovis | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mycobacterium tuberculosis Isocitrate lyase/ICL (Met1-His428). | ||||||||
| 타겟 | EC:4.1.3.1, ICL, Isocitrase, Isocitratase, Isocitrate lyase, icl | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P9WKK7 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||||||
| 제품 사용 정보 |
| ||||||||
| 배경 | Isocitrate lyase (ICL) is a ~47 kDa protein. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. It could also catalyze the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route). 1. Sharma, V. et al. (2000) Nature structural biology 7, 663-8. PMID: 10932251 2. McKinney, JD. et al. (2000) Nature 406, 735-8. PMID: 10963599 3. Kumar, R. et al. (2008) Proteins 72, 892-900. PMID: 18275086 4. Moynihan, MM. et al. (2014) Biochemistry 53, 178-87. PMID: 24354272 | ||||||||
| 참고사항 | For research use only. |
문의하기
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
