

| 카탈로그 번호 | HB628014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-WT1 Polyclonal Antibody (HB628014) is a rabbit polyclonal antibody detecting WT1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Pig, and Xenopus laevis.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human WT1 (Thr317-Gln446). | ||||||||
| 타겟 | WT1, Wilms tumor protein, WT33 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P19544 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Wilms tumor protein (WT1) is a ~49 kDa protein. Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. 1. Hamilton, TB. et al. (1995) Nucleic acids research 23, 277-84. PMID: 7862533 2. Stoll, R. et al. (2007) Journal of molecular biology 372, 1227-45. PMID: 17716689 3. Hashimoto, H. et al. (2014) Genes & development 28, 2304-13. PMID: 25258363 4. Smolen, GA. et al. (2004) Cancer research 64, 7846-51. PMID: 15520190 5. Markus, MA. et al. (2006) Experimental cell research 312, 3379-88. PMID: 16934801 6. Weiss, TC. et al. (2009) Biochemistry 48, 148-55. PMID: 19123921 | ||||||||
| 참고사항 | For research use only. |
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