InVivo Plus Anti-Mouse PD-L1 Antibody(10F.9G2) (MV974029)

Name: InVivo Plus Anti-Mouse PD-L1 Antibody(10F.9G2)
Brand: abinScience
SKU: MV974029
Price: 128 USD
Availability: InStock

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	MV974029
설명	InVivo Plus Anti-Mouse CD274/PD-L1/B7-H1 Antibody (10F.9G2) [10F.9G2] (MV974029) is a rat monoclonal antibody detecting Programmed cell death 1 ligand 1 in in vivo PD-L1 blockade, in vitro PD-L1 blockade, IF, IHC-F, FCM, WB. Suitable for Mouse. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
종 반응성	Mouse
응용 분야	in vivo PD-L1 blockade, in vitro PD-L1 blockade, IF, IHC-F, FCM, WB
숙주 종	Rat
클론성	Monoclonal
이소타입	IgG2b
클론 ID	10F.9G2
타겟	B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1
내독소 수준	< 1 EU/mg
순도	>95% as determined by SDS-PAGE.
관련 제품	pH 7.4 Dilution Buffer
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q9EP73
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경	Programmed cell death 1 ligand 1 (CD274/PD-L1) is a ~32 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10). CD274 is the therapeutic target of atezolizumab (Tecentriq) and durvalumab (Imfinzi). 1. Tamura, H. et al. (2001) Blood 97, 1809-16. PMID: 11238124 2. Freeman, GJ. et al. (2000) The Journal of experimental medicine 192, 1027-34. PMID: 11015443 3. Wang, S. et al. (2003) The Journal of experimental medicine 197, 1083-91. PMID: 12719480
참고사항	For research use only.
Isotype Control	Rat IgG2b Recombinant Isotype Control Antibody (LTF-2) (RF974107)

이미지

Bioactivity

Detects Recombinant Mouse CD274/PD-L1/B7-H1 Protein (Cat No.: MV974011) in indirect ELISA.
SDS-PAGE

SDS-PAGE for InVivo Plus Anti-Mouse CD274/PD-L1/B7-H1 Antibody (10F.9G2).