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Human CD94/KLRD1 Recombinant Protein (C-Fc) (HC299011)

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사양:
  • 50ug
  • 100ug
  • 1mg
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  • 개요

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개요
카탈로그 번호HC299011
설명
Recombinant Human CD94/KLRD1 Protein, C-Fc (HC299011) expressed in Mammalian Cells, spanning Lys32-Ile179. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템Mammalian cells
등록번호Q13241
단백질 길이Lys32-Ile179
응용 분야ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종Homo sapiens (Human)
성질 Recombinant
내독소 수준 Please contact with the lab for this information.
순도 >90% as determined by SDS-PAGE.
예측 분자량 45.50 kDa
형태 Lyophilized
저장 완충액 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

재구성 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름CD94, KLRD1, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, Natural killer cells antigen CD94
배경

Natural killer cells antigen CD94 is a ~20 kDa protein. Immune receptor involved in self-nonself discrimination. In complex with KLRC1 or KLRC2 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia and non-classical MHC class Ib molecules. Enables cytotoxic cells to monitor the expression of MHC class I molecules in healthy cells and to tolerate self. Primarily functions as a ligand binding subunit as it lacks the capacity to signal.

1. Boyington, JC. et al. (1999) Immunity 10, 75-82. PMID: 10023772
2. Bhagat, G. et al. (2008) The Journal of clinical investigation 118, 281-93. PMID: 18064301
3. Sullivan, LC. et al. (2007) Immunity 27, 900-11. PMID: 18083576
4. Lin, Z. et al. (2023) Nature immunology 24, 1087-1097. PMID: 37264229
5. Braud, VM. et al. (1998) Nature 391, 795-9. PMID: 9486650
6. Llano, M. et al. (1998) European journal of immunology 28, 2854-63. PMID: 9754572
7. Jabri, B. et al. (2002) Immunity 17, 487-99. PMID: 12387742
8. Valiante, NM. et al. (1997) Immunity 7, 739-51. PMID: 9430220
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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