

| 카탈로그 번호 | MT439022 |
|---|---|
| 설명 |
Recombinant Mouse CD254/RANKL/TNFSF11 Protein, N-His (MT439022) expressed in E. coli, spanning Arg72-Asp316. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | O35235 |
| 단백질 길이 | Arg72-Asp316 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Mus musculus (Mouse) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 29.86 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | CD254, ODF, OPGL, Osteoclast differentiation factor, Osteoprotegerin ligand, RANKL, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TNFSF11, TRANCE, Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor ligand superfamily member 11, membrane form, Tumor necrosis factor ligand superfamily member 11, soluble form |
| 배경 | Tumor necrosis factor ligand superfamily member 11 is a ~35 kDa protein. Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. 1. Linares, GR. et al. (2012) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 27, 1553-65. PMID: 22437732 2. Mahoney, DJ. et al. (2008) The Journal of biological chemistry 283, 25952-62. PMID: 18586671 3. Tiedemann, K. et al. (2013) Journal of cell science 126, 4187-94. PMID: 24039232 4. Omata, Y. et al. (2016) PloS one 11, e0157992. PMID: 27336669 5. Kim, H. et al. (2013) Cell metabolism 17, 249-60. PMID: 23395171 6. Decker, CE. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 15654-9. PMID: 26644563 |
| 참고사항 | For research use only |
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