



| 카탈로그 번호 | MC472012 |
|---|---|
| 설명 |
Recombinant Mouse IL24 Protein, N-His (MC472012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q925S4 |
| 단백질 길이 | Gln27-Leu181 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Mus musculus (Mouse) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | IL-24, IL-4-induced secreted protein, Il24, Interleukin-24, MDA-7, Mda7, Melanoma differentiation-associated gene 7 protein, Th2-specific cytokine FISP |
| 배경 | Interleukin-24 is a ~25 kDa protein. Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I interferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal. 1. Wang, J. et al. (2020) Cell death & disease 11, 17. PMID: 31907348 2. Davidson, S. et al. (2022) Science immunology 7, eabi6763. PMID: 35148201 |
| 참고사항 | For research use only |

SDS-PAGE for Recombinant Mouse IL24 Protein, N-His

Detected by Anti-Mouse IL24 antibody (SAA2230) (Catalog No: MC472013) in indirect ELISA




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