Mouse MAG/Siglec-4a Recombinant Protein (C-His) (MB948011)

Name: Mouse MAG/Siglec-4a Recombinant Protein (C-His)
Brand: abinScience
SKU: MB948011
Price: 298 USD
Availability: InStock

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100ug
1mg

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개요

카탈로그 번호	MB948011
설명	Recombinant Mouse MAG Protein, C-His (MB948011) expressed in Mammalian Cells, spanning Met1-Pro516. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	Mammalian cells
등록번호	P20917
단백질 길이	Met1-Pro516
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Mus musculus (Mouse)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	57.98 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	GMA, MAG, Myelin-associated glycoprotein, Siglec-4a
배경	Myelin-associated glycoprotein is a ~69 kDa protein. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2. Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis, also after injury; protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. Required to prevent degeneration of myelinated axons in adults; this probably depends on binding to gangliosides on the axon cell membrane. Negative regulator of neurite outgrowth that inhibits axon longitudinal growth. 1. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450 2. Pronker, MF. et al. (2016) Nature communications 7, 13584. PMID: 27922006 3. Kelm, S. et al. (1994) Current biology : CB 4, 965-72. PMID: 7533044 4. Schachner, M. et al. (2000) Glia 29, 154-65. PMID: 10625334 5. Li, C. et al. (1994) Nature 369, 747-50. PMID: 7516497 6. Bartsch, S. et al. (1997) Brain research 762, 231-4. PMID: 9262180 7. Li, C. et al. (1998) Journal of neuroscience research 51, 210-7. PMID: 9469574 8. Yin, X. et al. (1998) The Journal of neuroscience : the official journal of the Society for Neuroscience 18, 1953-62. PMID: 9482781 9. Fujita, N. et al. (1998) The Journal of neuroscience : the official journal of the Society for Neuroscience 18, 1970-8. PMID: 9482783 10. Palandri, A. et al. (2015) Cell death & disease 6, e1876. PMID: 26335717
참고사항	For research use only

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Mouse MAG/Siglec-4a Recombinant Protein (C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Mouse MAG/Siglec-4a Recombinant Protein (C-His) (MB948011)

개요

이미지

참고 문헌

데이터시트

SDS

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