

| 카탈로그 번호 | MP096011 |
|---|---|
| 설명 |
Recombinant Mouse RTN4R/NgR1/Nogor Protein, C-His (MP096011) expressed in Mammalian Cells, spanning Cys27-Ser447. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | Mammalian cells |
| 등록번호 | Q99PI8 |
| 단백질 길이 | Cys27-Ser447 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Mus musculus (Mouse) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 48.46 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | NOGOR, NgR, Nogo receptor, Nogo-66 receptor, RTN4R, Reticulon-4 receptor |
| 배경 | Reticulon-4 receptor is a ~50 kDa protein. Receptor for RTN4, OMG and MAG. Functions as a receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as a receptor for chondroitin sulfate proteoglycans. Can also bind heparin. Intracellular signaling cascades are triggered via the coreceptor NGFR. 1. Fournier, AE. et al. (2001) Nature 409, 341-6. PMID: 11201742 2. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450 3. Kim, JE. et al. (2004) Neuron 44, 439-51. PMID: 15504325 4. Williams, G. et al. (2008) The Journal of biological chemistry 283, 16641-52. PMID: 18411262 5. Nakaya, N. et al. (2012) The Journal of biological chemistry 287, 37171-84. PMID: 22923615 6. Dickendesher, TL. et al. (2012) Nature neuroscience 15, 703-12. PMID: 22406547 7. Wills, ZP. et al. (2012) Neuron 73, 466-81. PMID: 22325200 9. Palandri, A. et al. (2015) Cell death & disease 6, e1876. PMID: 26335717 |
| 참고사항 | For research use only |
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