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| 카탈로그 번호 | HY216016 | ||||
|---|---|---|---|---|---|
| 설명 |
Research Grade amesotatug (HY216016) is a human monoclonal antibody. Suitable for Human.
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| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1, kappa | ||||
| 타겟 | ANX1, ANXA1, Annexin A1, Annexin Ac2-26, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, LPC1, Lipocortin I, Phospholipase A2 inhibitory protein, p35 | ||||
| 내독소 수준 | < 10 EU/mg | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P04083 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Annexin A1 (ANXA1) is a ~38 kDa protein. Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T cells. Promotes the differentiation of T cells into Th1 cells and negatively regulates differentiation into Th2 cells. 1. Arcone, R. et al. (1993) European journal of biochemistry 211, 347-55. PMID: 8425544 2. D'Acquisto, F. et al. (2007) Blood 109, 1095-102. PMID: 17008549 3. McArthur, S. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 4000-10. PMID: 19625660 4. Pepinsky, RB. et al. (1989) The Biochemical journal 263, 97-103. PMID: 2532504 5. Mailliard, WS. et al. (1996) The Journal of biological chemistry 271, 719-25. PMID: 8557678 | ||||
| 참고사항 | For research use only. |
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