Anti-Human CCR5 Reference Antibody (HGS1025, RUO) (HW412036)

Name: Anti-Human CCR5 Reference Antibody (HGS1025, RUO)
Brand: abinScience
SKU: HW412036
Price: 370 USD
Availability: InStock

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개요

카탈로그 번호	HW412036
설명	Anti-Human CD195/CCR5 (HGS1025) (HW412036) is a research-grade recombinant antibody targeting CD195. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG
클론 ID	HGS1025
발현 시스템	Mammalian cells
타겟	C-C CKR-5, CC-CKR-5, CMKBR5, HIV-1 fusion coreceptor, CHEMR13, CCR5, C-C chemokine receptor type 5, CD195, CCR-5
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P51681
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	HGS1025
배경	C-C chemokine receptor type 5 (CD195/CCR5) is a ~40 kDa protein. Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor. 1. Sharapova, TN. et al. (2018) Acta naturae 10, 115-120. PMID: 30713770
참고사항	For research use only. Not suitable for clinical or therapeutic use.