Anti-Human FGFR4 Reference Antibody (U3-1784, RUO) (HB856016)

Name: Anti-Human FGFR4 Reference Antibody (U3-1784, RUO)
Brand: abinScience
SKU: HB856016
Price: 176 USD
Availability: InStock

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100ug
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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HB856016

설명

Anti-Human CD334/FGFR4 (U3-1784) (HB856016) is a research-grade recombinant antibody targeting CD334. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

종 반응성

Human

응용 분야

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

숙주 종

Human

클론성

Monoclonal

이소타입

IgG1

클론 ID

U3-1784

발현 시스템

Mammalian cells

타겟

FGFR4, Fibroblast growth factor receptor 4, TKF, FGFR-4, JTK2, CD334

내독소 수준

< 10 EU/mg

순도

>95% purity as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P22455

형태

Liquid

저장 완충액

0.01M PBS pH 7.4

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

대체 이름

U3-1784

배경

Fibroblast growth factor receptor 4 (CD334/FGFR4) is a ~87 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.

참고사항

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1, lambda Isotype Control antibody (HyHEL-10) (HP248107)

이미지

SDS-PAGE

SDS-PAGE for Anti-Human FGFR4 Reference Antibody (U3-1784, RUO)

참고 문헌

데이터시트

Anti-Human FGFR4 Reference Antibody (U3-1784, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human FGFR4 Reference Antibody (U3-1784, RUO) (HB856016)

개요

이미지

참고 문헌

데이터시트

SDS

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