Anti-Human CD94 Reference Antibody (Dibotatug, RUO) (HC299016)

Name: Anti-Human CD94 Reference Antibody (Dibotatug, RUO)
Brand: abinScience
SKU: HC299016
Price: 336 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HC299016
설명	Dibotatug (HC299016) is a research-grade recombinant antibody targeting CD94. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1-kappa
발현 시스템	Mammalian cells
타겟	Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, Natural killer cells antigen CD94, CD94, KP43, KLRD1
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q13241
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	2842038-48-4
배경	Natural killer cells antigen CD94 (KLRD1) is a ~20 kDa protein. Immune receptor involved in self-nonself discrimination. In complex with KLRC1 or KLRC2 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia and non-classical MHC class Ib molecules. Enables cytotoxic cells to monitor the expression of MHC class I molecules in healthy cells and to tolerate self. Primarily functions as a ligand binding subunit as it lacks the capacity to signal. 1. Boyington, JC. et al. (1999) Immunity 10, 75-82. PMID: 10023772 2. Bhagat, G. et al. (2008) The Journal of clinical investigation 118, 281-93. PMID: 18064301 3. Sullivan, LC. et al. (2007) Immunity 27, 900-11. PMID: 18083576 4. Lin, Z. et al. (2023) Nature immunology 24, 1087-1097. PMID: 37264229 5. Braud, VM. et al. (1998) Nature 391, 795-9. PMID: 9486650 6. Llano, M. et al. (1998) European journal of immunology 28, 2854-63. PMID: 9754572 7. Jabri, B. et al. (2002) Immunity 17, 487-99. PMID: 12387742 8. Valiante, NM. et al. (1997) Immunity 7, 739-51. PMID: 9430220
참고사항	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

이미지

SDS-PAGE

SDS-PAGE for Research Grade Dibotatug.
Bioactivity

Detects recombinant CD94 (Catalog No: HC299012) in indirect ELISA.

참고 문헌

데이터시트

Anti-Human CD94 Reference Antibody (Dibotatug, RUO).pdf

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Formula

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Anti-Human CD94 Reference Antibody (Dibotatug, RUO) (HC299016)

개요

이미지

참고 문헌

데이터시트

SDS

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